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Submitted: 20 Aug 2023
Accepted: 30 Sep 2023
ePublished: 29 Dec 2023
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Avicenna J Environ Health Eng. 2023;10(2): 72-77.
doi: 10.34172/ajehe.5402
  Abstract View: 582
  PDF Download: 252

Original Article

Cefixime Removal from Aqueous Solutions by Granular Ferric Oxide (GFO): Modeling and Optimization

Mahdi Asadi-Ghalhari 1 ORCID logo, Fatemeh Ranjdoost 2* ORCID logo, Fatemeh Sadat Tabatabaei 3 ORCID logo, Roqiyeh Mostafaloo 4 ORCID logo, Hassan Izanloo 5 ORCID logo, Nasim Ghafouri 6 ORCID logo, Alireza Omidi Oskouei 7, Somaye Behnamipour 5 ORCID logo, Reza Ansari 8 ORCID logo

1 Department of Environmental Health Engineering, Faculty of Health, Research Center for Environmental Pollutants, Qom University of Medical Sciences, Qom, Iran
2 Student Research Committee, Qom University of Medical Sciences, Qom, Iran
3 Department of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran
4 Department of Environmental Health Engineering, School of Public Health and Research Center for Health Sciences, Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran
5 Research Center for Environmental Pollutants, Qom University of Medical Sciences, Qom, Iran
6 Department of Environmental Health Engineering, Alborz University of Medical Sciences, Alborz, Iran
7 Department of Public Health, Faculty of Health, Qom University of Medical Sciences, Qom, Iran
8 Monitoring Center for Water and Sewage Quality, Department of Water and Wastewater, Qom, Iran
*Corresponding Author: Fatemeh Ranjdoost, Email: fatemehrnj77@gmail.com, Email: fatemehrnj77@gmail.com

Abstract

In recent years, the presence of various pharmaceutical residues such as cefixime (CFX) in aquatic environments has been gaining attention due to its adverse effects on health and ecosystems. Since conventional treatment methods are unable to remove antibiotics, sustainable and efficient approaches are needed to remove these compounds from aquatic environments. In this study, granular ferric oxide (GFO) was used to remove CFX, and the experiments were designed using Design Expert software. The findings were then analyzed using ANOVA test. The results showed that the proposed regression model fit the experimental condition (R2=0.9701, R2 adjusted=0.9432, R2 predicted=0.83). Several residual plots were used to confirm the suitability of the model. The initial concentration of 1.84 mg/L, GFO dose of 3.05 mg/L, and contact time of 24.32 minutes were found to be the ideal conditions for CFX adsorption. Moreover, the findings showed that GFO can be effective in absorbing and removing CFX from aqueous environments.

Please cite this article as follows: Asadi-Ghalhari M, Ranjdoost F, Tabatabaei FS, Mostafaloo R, Izanloo H, Ghafouri N, et al. Cefixime removal from aqueous solutions by granular ferric oxide (GFO): modeling and optimization. Avicenna J Environ Health Eng. 2023; 10(2):72-77. doi:10.34172/ajehe.5402
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