Hamadan University of Medical Sciences Avicenna Journal of Environmental Health Engineering 2423-4583 11 1 2024 06 29 Impact of Heavy Metal Pollution on Oxidized Low-density Lipoprotein Levels among Car Maintenance Workshop Workers 12 18 10.34172/ajehe.5443 EN Mustafa Fuad Khalid https://orcid.org/0000-0002-1513-9350 Nada A. Kadhim https://orcid.org/0000-0003-4718-3871 Journal Article 10.34172/ajehe.5443 2023 12 23 2024 05 06 This study aimed to evaluate the relationship between heavy metal pollution and oxidized low-density lipoprotein (OxLDL) among workers in car maintenance workshops in Baghdad, Iraq. Blood samples were collected from 70 male workers, including car maintenance and vehicle painting workers, along with a control group of healthy males. The levels of heavy metals, specifically cadmium (Cd) and lead (Pb), as well as OxLDL and the marker of lipid peroxidation, malondialdehyde (MDA), were measured. The results revealed a significant increase in the level of Pb in the blood of workers compared to the control group, whereas Cd levels did not exhibit a significant difference. Furthermore, both groups of workers exhibited significantly elevated levels of OxLDL compared to the control group. Additionally, the MDA level was significantly increased across all the study groups. Correlation analysis demonstrated positive associations between OxLDL levels and the extent of Pb and Cd pollution in the car maintenance worker group. These findings indicate an increased risk of developing cardiovascular diseases (CVDs) among workers in car maintenance workshops due to exposure to heavy metals. The observed elevation in the levels of OxLDL and lipid peroxidation markers underscores the potential health issues associated with occupational exposure to these polluted environments.