Hamadan University of Medical Sciences Avicenna Journal of Environmental Health Engineering 2423-4583 11 2 2024 12 29 Carcinogenicity and Non-carcinogenicity Effects of Heavy Metals in Consumed Bread in Zahedan, Iran 82 90 10.34172/ajehe.5370 EN Fatemeh Tabatabae https://orcid.org/0000-0001-7579-1944 Seyed Davoud Ashrafi https://orcid.org/0000-0002-9726-5456 Reza Ghanbari https://orcid.org/0000-0002-8061-4912 Hossein Ansari https://orcid.org/0000-0003-2755-7864 Hossein Kamani https://orcid.org/0000-0002-1498-9580 Leili Mohammadi https://orcid.org/0000-0003-1979-4800 Muhammad Nadeem Zafar https://orcid.org/0000-0002-2109-7601 Abdollah Dargahi https://orcid.org/0000-0003-2929-2556 Mojdeh Jahantigh https://orcid.org/0000-0001-7381-5882 Journal Article 10.34172/ajehe.5370 2023 05 13 2024 12 22 The effect of environmental pollution on contamination and the safety of foods for human consumption is a serious global issue, which has been widely addressed. Heavy metals are among the most frequent environmental pollutants that are extremely health-threatening. This cross-sectional study aimed at investigating the heavy metal content in different types of bread used in Zahedan, Southeastern Iran. A total of 36 different bread types, such as Sangak, Lavash, and Taftoon, baked by bakeries in Zahedan, were examined for various heavy metals (cadmium, lead, chromium, arsenic, copper, cobalt, mercury, zinc, and nickel) by inductively coupled plasma-optical emission spectrometry. The hazard quotient (HQ) of Taftoon, Lavash, and Sangak was<1 in males, females, and children. In addition, the total health risk of the nine studied heavy metals had a ranking order of HIchildren>HIfemales>HImales>1, demonstrating an increasing potential. The total carcinogenic risk factor for bread was 9.98×10-5 and 3.26×10-3 in males and females, respectively. Regarding the carcinogenicity of heavy metals in bread samples collected in Zahedan, it is highly recommended that measures, such as implementing a food control system, proper flour storage, and training farmers, should promptly be taken to reduce contamination.